New UKGTN Genetic Test Recommendations for NHS Service from 2015

Written by Jacqui Hoyle on 15 October 2014

The UKGTN Clinical and Scientific Advisory Group (CSAG) met on September 16th 2014 and has recommended 45 new tests for NHS service from April 2015 of which:

  • 38 are prescribed services and 7 are within Highly Specialised Services
  • 11 were evaluated through the very rare disease process (less than 20 index cases a year and less than £5000 annual costs for index cases)
  • 23 are new panel tests that use Next Generation Sequencing (NGS)
  • 2 are for tests using non-invasive prenatal diagnosis (NIPD) technology

Please access this summary report for further details of these recommendations including financial implications.  Further information of the 45 new tests including the provider lab is listed in this table. Potential savings are a mixture of actual savings (e.g. NGS replacing Sanger sequencing) and efficiencies as they release capacity for alternative use in the NHS (e.g. MRI no longer required for clinical diagnosis). The savings in medical genetics is due to less index activity and the lower cost of testing family members. The clinical benefits of these tests is summarised here.   

The test service information, Gene Dossiers and Testing Criteria will be uploaded to the on-line database by the end of December 2014.